Lawson, Alastair D.G. : rechercher sur Z-Library

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Articles (58)
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[American Institute of Aeronautics and Astronautics AIAA Flight Testing Conference - Denver, Colorado ()] AIAA Flight Testing Conference - The aircraft spin - a mathematical approach and comparison to flight test

Bennett, Christopher J., Lawson, Nicholas, Gautrey, Jim, Cooke, Alastair

Langue:

english

Fichier:

PDF, 1009 KB

english

Rings in Drugs

Taylor, Richard D., MacCoss, Malcolm, Lawson, Alastair D. G.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2014

Analysis of heavy and light chain sequences of conventional camelid antibodies from Camelus dromedarius and Camelus bactrianus species

Griffin, Laura M., Snowden, James R., Lawson, Alastair D.G., Wernery, Ulrich, Kinne, Jorg, Baker, Terry S.

Journal:

Journal of Immunological Methods

Année:

2014

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2014

Reviews

Lawson, Andrew, Jacobus, Mary, Docherty, Thomas, Latimer, Dan, Fendt, Gene, Blake, N. F., Hamer, Mary, Copley, Stephen, Williams, Alastair, Hirschkop, Ken, Neill, Edward

Journal:

Textual Practice

Année:

1989

Langue:

english

Fichier:

PDF, 3.94 MB

english, 1989

Multimerization behaviour of single chain Fv variants for the tumour-binding antibody B72.3

Desplancq, Dominique, King, David J., Lawson, Alastair D.G., Mountain, Andrew

Journal:

Protein Engineering Design and Selection

Année:

1994

Langue:

english

Fichier:

PDF, 2.09 MB

english, 1994

Combining Molecular Scaffolds from FDA Approved Drugs: Application to Drug Discovery

Taylor, Richard D., MacCoss, Malcolm, Lawson, Alastair D. G.

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2017

Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation

Glatt, Sophie, Baeten, Dominique, Baker, Terry, Griffiths, Meryn, Ionescu, Lucian, Lawson, Alastair D G, Maroof, Ash, Oliver, Ruth, Popa, Serghei, Strimenopoulou, Foteini, Vajjah, Pavan, Watling, Mark

Journal:

Annals of the Rheumatic Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2017

Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies

Macpherson, Alex, Scott-Tucker, Anthony, Spiliotopoulos, Anastasios, Simpson, Catherine, Staniforth, Justin, Hold, Adam, Snowden, James, Manning, Leah, van den Elsen, Jean, Lawson, Alastair D. G., Nem

Journal:

PLoS Biology

Année:

2020

Fichier:

PDF, 3.05 MB

2020

Blockade of colony stimulating factor-1 (CSF-1) leads to inhibition of DSS-induced colitis

Diane Marshall, James Cameron, Daniel Lightwood, Alastair D.G. Lawson

Journal:

Inflammatory Bowel Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22

John F. DiJoseph, Andrew Popplewell, Simon Tickle, Heather Ladyman, Alastair Lawson, Arthur Kunz, Kiran Khandke, Douglas C. Armellino, Erwin R. Boghaert, Philip R. Hamann, Karen Zinkewich-Peotti, Sue

Journal:

Cancer Immunology, Immunotherapy

Année:

2005

Langue:

english

Fichier:

PDF, 463 KB

english, 2005

Comparison of Naturally Occurring Human Immunoglobulin Sequences with the Anti-TNF Agents Certolizumab Pegol, Adalimumab, and Infliximab

Andrew Martin, Kerry Tyson, Matt Page, Gianluca Fossati, James Snowden, Raghavan Abhinandan, Alastair Lawson, Andrew Nesbitt, Andrew Popplewell

Journal:

Clinical Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 57 KB

english, 2007

Antibody generation through B cell panning on antigen followed by in situ culture and direct RT-PCR on cells harvested en masse from antigen-positive wells

Daniel J. Lightwood, Bruce Carrington, Alistair J. Henry, Andrew J. McKnight, Kenneth Crook, Karen Cromie, Alastair D.G. Lawson

Journal:

Journal of Immunological Methods

Année:

2006

Langue:

english

Fichier:

PDF, 553 KB

english, 2006

Spatial and mechanical controls on normal fault populations

Steven D. Knott, Alastair Beach, Paul J. Brockbank, J. Lawson Brown, Jean E. McCallum, Alastair I. Welbon

Journal:

Journal of Structural Geology

Année:

1996

Langue:

english

Fichier:

PDF, 1.57 MB

english, 1996

Cisplatin and carboplatin: a guide to administration

NORA LAWSON, DUNCAN JODRELL, ALASTAIR McMURRAY

Journal:

European Journal of Cancer Care

Année:

1993

Langue:

english

Fichier:

PDF, 387 KB

english, 1993

Relative stabilities of IgG1 and IgG4 Fab domains: Influence of the light–heavy interchain disulfide bond architecture

James T. Heads, Ralph Adams, Lena E. D'Hooghe, Matt J. T. Page, David P. Humphreys, Andrew G. Popplewell, Alastair D. Lawson, Alistair J. Henry

Journal:

Protein Science

Année:

2012

Langue:

english

Fichier:

PDF, 148 KB

english, 2012

Amino acid sequence at the major phosphorylation site on bovine kidney branched-chain 2-oxoacid dehydrogenase complex

Kenneth G. Cook, Rowena Lawson, Stephen J. Yeaman, Alastair Aitken

Journal:

FEBS Letters

Année:

1983

Langue:

english

Fichier:

PDF, 379 KB

english, 1983

Co-expression of human protein disulphide isomerase (PDI) can increase the yield of an antibody Fab′ fragment expressed in Escherichia coli

David P. Humphreys, Neil Weir, Alastair Lawson, Andrew Mountain, Peter A. Lund

Journal:

FEBS Letters

Année:

1996

Langue:

english

Fichier:

PDF, 438 KB

english, 1996

Modulation of CSF-1-regulated post-natal development with anti-CSF-1 antibody

Suwen Wei, Daniel Lightwood, Heather Ladyman, Sue Cross, Helen Neale, Meryn Griffiths, Ralph Adams, Diane Marshall, Alastair Lawson, Andrew J. McKnight, E. Richard Stanley

Journal:

Immunobiology

Année:

2005

Langue:

english

Fichier:

PDF, 776 KB

english, 2005

A plasmid system for optimization of Fab′ production in Escherichia coli: importance of balance of heavy chain and light chain synthesis

David P Humphreys, Bruce Carrington, Leigh C Bowering, Ravindra Ganesh, Mukesh Sehdev, Bryan J Smith, Lloyd M King, Dominic G Reeks, Alastair Lawson, Andrew G Popplewell

Journal:

Protein Expression and Purification

Année:

2002

Langue:

english

Fichier:

PDF, 479 KB

english, 2002

Antibody-enabled small-molecule drug discovery

Lawson, Alastair D. G.

Journal:

Nature Reviews Drug Discovery

Année:

2012

Langue:

english

Fichier:

PDF, 568 KB

english, 2012

Immunoassays for the Detection of Human Collagenase, Stromelysin, Tissue Inhibitor of Metallo-proteinases (TIMP) and Enzyme-Inhibitor Complexes

Cooksley, Susan, Hipkiss, Jayne B., Tickle, Simon P., Holmes-Ievers, Eileen, Docherty, Andrew J.P., Murphy, Gillian, Lawson, Alastair D.G.

Journal:

Matrix - Collagen and Related Research

Année:

1990

Langue:

english

Fichier:

PDF, 986 KB

english, 1990

Tu1762 Absence of Gut Microbiota Reduces Lipopolysaccharide-Induced Epithelial Cell Shedding in the Small Intestine

Hughes, Kevin R., Alcon-Giner, Cristina, Lawson, Melissa, McCoy, Kathy D., Macpherson, Andrew J., Hall, Lindsay J., Watson, Alastair J.

Journal:

Gastroenterology

Année:

2014

Langue:

english

Fichier:

PDF, 146 KB

english, 2014

Anabolic Steroids

Mcdonald, Lawson, Baker, Carole, Bray, Colin, Mcdonald, Alastair, Restieaux, Norma

Journal:

The Lancet

Année:

1958

Langue:

english

Fichier:

PDF, 170 KB

english, 1958

PLASMA-CATECHOLAMINES AFTER CARDIAC INFARCTION

Mcdonald, Lawson, Baker, Carole, Bray, Colin, Mcdonald, Alastair, Restieaux, Norma

Journal:

The Lancet

Année:

1969

Langue:

english

Fichier:

PDF, 419 KB

english, 1969

SYSTEMIC HYPERTENSION AFTER HOMOGRAFT AORTIC VALVAR REPLACEMENT A CAUSE OF LATE HOMOGRAFT FAILURE

Layton, Clive, Brigden, Wallace, Mcdonald, Lawson, Monro, James, Mcdonald, Alastair, Weaver, John

Journal:

The Lancet

Année:

1973

Langue:

english

Fichier:

PDF, 631 KB

english, 1973

APPARATUS FOR RECORDING ELECTROCARDIOGRAMS, INCORPORATING AUTOMATIC SEARCH AND HIGH-SPEED PLAYBACK

Maloy, William, Mcdonald, Alastair, Mcdonald, Lawson, Norman, John, Obeyesekera, Piyasena, Resnekov, Leon

Journal:

The Lancet

Année:

1968

Langue:

english

Fichier:

PDF, 464 KB

english, 1968

Purification of recombinant chimeric B72.3 Fab′ and F(ab′)2 using streptococcal protein G

Proudfoot, Karen A., Torrance, Christopher, Lawson, Alastair D.G., King, David J.

Journal:

Protein Expression and Purification

Année:

1992

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1992

HOMOGRAFT REPLACEMENT OF THE AORTIC VALVE

Mcdonald, Alastair, Mcdonald, Lawson, Resnekov, Leon, Robinson, Michael, Ross, Donald

Journal:

The Lancet

Année:

1968

Langue:

english

Fichier:

PDF, 1.22 MB

english, 1968

Prolonged in Vivo Residence Times of Antibody Fragments Associated with Albumin

Smith, Bryan J., Popplewell, Andrew, Athwal, Dee, Chapman, Andrew P., Heywood, Sam, West, Shauna M., Carrington, Bruce, Nesbitt, Andrew, Lawson, Alastair D. G., Antoniw, Pari, Eddelston, Alison, Suitt

Journal:

Bioconjugate Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 89 KB

english, 2001

Creation of a gated antibody as a conditionally functional synthetic protein

Gunnoo, Smita B., Finney, Helene M., Baker, Terry S., Lawson, Alastair D., Anthony, Daniel C., Davis, Benjamin G.

Journal:

Nature Communications

Année:

2014

Langue:

english

Fichier:

PDF, 992 KB

english, 2014

Functional inhibition of β-catenin-mediated Wnt signaling by intracellular VHH antibodies

Newnham, Laura E, Wright, Michael J, Holdsworth, Gill, Kostarelos, Kostas, Robinson, Martyn K, Rabbitts, Terence H, Lawson, Alastair D

Journal:

mAbs

Année:

2015

Langue:

english

Fichier:

PDF, 850 KB

english, 2015

Conformational Heterogeneity in Antibody-Protein Antigen Recognition

Addis, Philip W., Hall, Catherine J., Bruton, Shaun, Veverka, Vaclav, Wilkinson, Ian C., Muskett, Frederick W., Renshaw, Philip S., Prosser, Christine E., Carrington, Bruce, Lawson, Alastair D. G., Gr

Journal:

Journal of Biological Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 3.02 MB

english, 2014

High-Throughput Screening for High Affinity Antibodies

Tickle, Simon, Adams, Ralph, Brown, Derek, Griffiths, Meryn, Lightwood, Daniel, Lawson, Alastair

Journal:

Journal of the Association for Laboratory Automation

Année:

2009

Langue:

english

Fichier:

PDF, 292 KB

english, 2009

Antibody Fragments Defining Biologically Relevant Conformations of Target Proteins

Lawson, Alastair

Journal:

Antibodies

Année:

2014

Langue:

english

Fichier:

PDF, 385 KB

english, 2014

Kinetics of functionalised carbon nanotube distribution in mouse brain after systemic injection: Spatial to ultra-structural analyses

Wang, Julie T.-W., Rubio, Noelia, Kafa, Houmam, Venturelli, Enrica, Fabbro, Chiara, Ménard-Moyon, Cécilia, Da Ros, Tatiana, Sosabowski, Jane K., Lawson, Alastair D., Robinson, Martyn K., Prato, Mauriz

Journal:

Journal of Controlled Release

Année:

2015

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2015

Sagittal Joint Kinematics, Moments, and Powers Are Predominantly Characterized by Speed of Progression, Not Age, in Normal Children

Stansfield, Ben W., Hillman, Susan J., Hazlewood, M. Elizabeth, Lawson, Alastair A., Mann, Alison M., Loudon, Ian R., Robb, James E.

Journal:

Journal of Pediatric Orthopaedics

Année:

2001

Langue:

english

Fichier:

PDF, 471 KB

english, 2001

Normalized Speed, Not Age, Characterizes Ground Reaction Force Patterns in 5-to 12-Year-Old Children Walking at Self-Selected Speeds

Stansfield, Ben W., Hillman, Susan J., Hazlewood, M. Elizabeth, Lawson, Alastair A., Mann, Alison M., Loudon, Ian R., Robb, James E.

Journal:

Journal of Pediatric Orthopaedics

Année:

2001

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2001

Extending the half-life of a Fab fragment through generation of a humanized anti-human serum albumin Fv domain: an investigation into the correlation between affinity and serum half-life

Adams, Ralph, Griffin, Laura, Compson, Joanne E., Jairaj, Mark, Baker, Terry, Ceska, Tom, West, Shauna, Zaccheo, Oliver, Davé, Emma, Lawson, Alastair D G., Humphreys, David P., Heywood, Sam

Journal:

mAbs

Année:

2016

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2016

10.1097/00004694-200105000-00026

Stansfield, Ben, Hillman, Susan, Hazlewood, M., Lawson, Alastair, Mann, Alison, Loudon, Ian, Robb, James

Journal:

Journal of Pediatric Orthopaedics

Année:

2001

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2001

10.1097/00004694-200105000-00027

Stansfield, Ben, Hillman, Susan, Hazlewood, M., Lawson, Alastair, Mann, Alison, Loudon, Ian, Robb, James

Journal:

Journal of Pediatric Orthopaedics

Année:

2001

Langue:

english

Fichier:

PDF, 471 KB

english, 2001

In Vitro Comparison of Three Different Chimeric Receptor-modified Effector T-cell Populations for Leukemia Cell Therapy

Pizzitola, Irene, Agostoni, Valentina, Cribioli, Elisabetta, Pule, Martin, Rousseau, Raphael, Finney, Helene, Lawson, Alastair, Biondi, Andrea, Biagi, Ettore, Marin, Virna

Journal:

Journal of Immunotherapy

Année:

2011

Langue:

english

Fichier:

PDF, 403 KB

english, 2011

Primary sequence of the N -terminal region of the α-subunit of pyruvate dehydrogenase from bovine heart

LAWSON, ROWENA, AITKEN, ALASTAIR, YEAMAN, STEPHEN J.

Journal:

Biochemical Society Transactions

Année:

1983

Langue:

english

Fichier:

PDF, 362 KB

english, 1983

Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product.

Finney, Helene M, Lawson, Alastair D G, Christopher, R, Weir, a Neil C, Bebbington, C R, Weir, a Neil C

Journal:

The Journal of Immunology

Année:

1998

Langue:

english

Fichier:

PDF, 325 KB

english, 1998

Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping

Liu, Xiaofeng, Taylor, Richard D., Griffin, Laura, Coker, Shu-Fen, Adams, Ralph, Ceska, Tom, Shi, Jiye, Lawson, Alastair D. G., Baker, Terry

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2017

Regressor time-shifting to identify longitudinal stability and control derivatives of the Jetstream 3102

Yusuf, Sezsy, Lone, Mudassir, Cooke, Alastair, Lawson, Nicholas

Journal:

Aerospace Science and Technology

Année:

2017

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2017

Natural Conformational Sampling of Human TNF α Visualized by Double Electron-Electron Resonance

Carrington, Bruce, Myers, William K., Horanyi, Peter, Calmiano, Mark, Lawson, Alastair D.G.

Journal:

Biophysical Journal

Année:

2017

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2017

On the Importance of Rigidity in Designing Small Molecule Drugs to Tackle Protein-Protein Interactions (PPIs) through Stabilisation of Desired Confomers

Lawson, Alastair D.G., MacCoss, Malcolm, Heer, Jag P.

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2017

Opportunities for Conformation-Selective Antibodies in Amyloid-Related Diseases

Westwood, Marta, Lawson, Alastair

Journal:

Antibodies

Année:

2015

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2015

Small Molecule Targeting of Protein–Protein Interactions through Allosteric Modulation of Dynamics

Cossins, Benjamin, Lawson, Alastair

Journal:

Molecules

Année:

2015

Langue:

english

Fichier:

PDF, 667 KB

english, 2015

The rational design of affinity attenuated OmCI for the purification of Complement C5

Macpherson, Alex, Liu, Xiaofeng, Dedi, Neesha, Kennedy, Jeffery, Carrington, Bruce, Durrant, Oliver, Heywood, Sam, van den Elsen, Jean, Lawson, Alastair D. G.

Journal:

Journal of Biological Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2018